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There is a way to cut the distance you have to travel. Get to the Daily Bugle. Get in between two smoke towers. You can use your Spider-Sense to find it. Look in the direction you want to go, then press Square and tap Left Analog-stick Down.

To easily defeat enemies jump then keep tapping both Attack buttons.

When an enemy is running away from you, press Circle. You will stun their eye and make it easier to kill them.

As Black suit Spider-Man, use your slow motion to dodge the King-Pin's attacks. Build up your "Rage Mode". Once in "Rage Mode" you can attack as normal.

To defeat Venom in the grand finale mission, hold L1 and run and hit the boxes which drive him crazy. By holding L1 while doing this, you will have more time to run while your opponent is in slow motion.

You can't take a bridge to the other side because of invisible barriers. I have found a way to get past them. However, you are very limited to what you can do. First, go to the Manhattan Bridge because it is a long one. Go within barriers and be on the side of the bridge where cars are heading to the barrier and beyond (right side). Jump on one of the cars and immediately enter Photo Mode. Hopefully, the car will continue driving and will drive past the barrier. You are still alive and are able to move around, zoom in, and take photos. You cannot leave Photo Mode because you will be catapulted back to the barrier. You can go as far as the other borough that is heavily lighted in the night time. At a certain point (usually when the bridge ends), you will reach a gray screen, and the only thing you can do is push the Start button and start over.

To get angry without having do fight enemies, simply tap R1 repeatedly. Spider-Man will make a shaking hand motion and will scream. The longer you tap R1, the more rage you will build up.

Defeat the New Goblin in his first battle to unlock him as a playable character.

If you go to a crime area that is already been taken over by the police, you may still answer, but it will be challenges with a random gang. Note that nothing will happen to the area once you complete the mission.

While swinging through the city you might hear a chime. This indicates that you are close to a token.

Complete the game.

Beat the Grand Finale Mission.

Beat New Goblin/Harry to unlock him for gameplay. Note: This only works for the collector's edition of Spiderman 3.

Successfully complete the game as Spider-Man to unlock Symbiote Spider-Man's story mode.

When you are fighting venom press L1 while you are breaking it at the same time for everyone you do. And that will unlock venom for free roam.

Go to the daily bugle and use your spidey sense to find to smoke towers. Then go slightly in between them and press square. then it will tell you to move the left analog stick down multiple times. then you will fly great distances. This is useful to get around the city faster. First try both directions out and then plan when you want to use them in missions. Or just use it for fun.

You can earn upgrades for this ability by using it a lot.