Well, to get to Sedona (normally without any rune goodies, I mean).
You have to save the druids who live in the Highlands first, To save it, talk to a man who live in the southeast of Highlands, his house is near a cave. When you talk to him, he'll ask you to take back her glass eyes from his brother in the south, wich mean Lowland.
Go to Lowland and go all over south, when you see a fence, go through it and you'll find a cave in the right of you. Go through that cave and find a ladder up. Climb that ladder and go all over north to the exit, and enter another cave just near that exit. manage your way there, and you'll find another exit with a bridge near it. Go through that bridge and you'll find a place name mystery manor. Enter that house (it's realy look like a house), and you'll found a lot of guy wandering there. Those guys are your enemy. manage your way to the top of the building where the man's brother standing there waiting (or actualy he don't realy want you to be there) you. Fight him and bring the eye back to the man in Highlands. He'll open a gate to the cave near his house and in that house you can found the daeva. Well, after you fought the daeva, as usual, bring the druids soul to it's body, and you'll receive a merchant ticket that you can use to enter the pennisula trade route. From that route just follow all the way west till you found a mule express and not far from it, there's Sedona.